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Article

GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.

The Journal of cell biology - 1 Jun 1993

Piper R C, Tai C, Kulesza P, Pang S, Warnock D, Baenziger J, Slot J W, Geuze H J, Puri C, James D E

Abstract excerpt

Expression of chimeras, composed of portions of two different glucose transporter isoforms (GLUT-1 and GLUT-4), in CHO cells had indicated that the cytoplasmic NH2 terminus of GLUT-4 contains important targeting information that mediates intracellular sequestration of this isoform (Piper, R. C., C. Tai, J. W. Slot, C. S. Hahn, C. M. Rice, H. Huang, D. E. James. 1992. J. Cell Biol. 117:729-743). In the present...

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PMID: 8509445
DOI: 10.1083/jcb.121.6.1221
PMCID: PMC2119717

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