Article
Roles of the N- and C-termini of GLUT4 in endocytosis.
Journal of cell science - 1 Jan 2002
Al-Hasani Hadi, Kunamneni Raghu K, Dawson Kevin, Hinck Cynthia S, Müller-Wieland Dirk, Cushman Samuel W
Abstract excerpt
In insulin target cells, the predominantly expressed glucose transporter isoform GLUT4 recycles between distinct intracellular compartments and the plasma membrane. To characterize putative targeting signals within GLUT4 in a physiologically relevant cell type, we have analyzed the trafficking of hemagglutinin (HA)-epitope-tagged GLUT4 mutants in transiently transfected primary rat adipose cells. Mutation of the...
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