Article
Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence.
Cell - 12 Jan 1996
García Véscovi E, Soncini F C, Groisman E A
Abstract excerpt
Ions are not traditionally thought to act as first messengers in signal transduction cascades. However, while searching for genes regulated by the PhoP/PhoQ virulence regulatory system of Salmonella typhimurium, we recovered two loci whose expression is controlled by the concentration of Mg2+. To...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cations
- Gene Expression Regulation, Bacterial
- Hydrogen-Ion Concentration
- Kinetics
- Magnesium
- Molecular Sequence Data
- Mutation
- Peptides
- Phenotype
- Protein Conformation
- Salmonella typhimurium
- Sensitivity and Specificity
- Signal Transduction
- Transcription Factors
- Virulence