Article
Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence.
Cell - 12 Jan 1996
García Véscovi E, Soncini F C, Groisman E A
Abstract excerpt
Ions are not traditionally thought to act as first messengers in signal transduction cascades. However, while searching for genes regulated by the PhoP/PhoQ virulence regulatory system of Salmonella typhimurium, we recovered two loci whose expression is controlled by the concentration of Mg2+. To determine whether Mg2+ is the signal modulating the whole PhoP/PhoQ system, we evaluated the gene expression pattern...
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