Article
Micronuclei induced by modulators of methylation: analogs of 5-azacytidine.
Carcinogenesis - 1 Jul 1995
Stopper H, Körber C, Gibis P, Spencer D L, Caspary W J
Abstract excerpt
Jones and coworkers demonstrated a qualitative correlation between 5-azacytidine and some of its analogs in inducing changes in cell morphology and their ability in preventing DNA methylation. Previously, we evaluated the same compounds to determine their ability to induce trifluorothymidine (TFT) resistance in L5178Y mouse cells and found that their mutagenic potency also correlated with their reported ability...
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