Micronuclei induced by modulators of methylation: analogs of 5-azacytidine.

doi:10.1093/carcin/16.7.1647

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Article

Micronuclei induced by modulators of methylation: analogs of 5-azacytidine.

Carcinogenesis - 1 Jul 1995

Stopper H, Körber C, Gibis P, Spencer D L, Caspary W J

Abstract excerpt

Jones and coworkers demonstrated a qualitative correlation between 5-azacytidine and some of its analogs in inducing changes in cell morphology and their ability in preventing DNA methylation. Previously, we evaluated the same compounds to determine their ability to induce trifluorothymidine (TFT...

Topics

Animals
Antimetabolites, Antineoplastic
Azacitidine
Deoxycytidine
Leukemia L5178
Methylation
Mice
Mice, Inbred C3H
Micronuclei, Chromosome-Defective
Micronucleus Tests
Mutation

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