Induction of the CD1a Langerhans cell marker on human monocytes.

doi:10.1016/0003-9969(94)00152-2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Induction of the CD1a Langerhans cell marker on human monocytes.

Archives of oral biology - 1 Feb 1995

Athanasas-Platsis S, Savage N W, Winning T A, Walsh L J

Abstract excerpt

Monocytes have recently been recognized as a precursor of Langerhans cells. This study examined the regulatory influence of the epithelial environment on the putative first step of the transition towards a Langerhans cell phenotype--the induction of CD1a antigen. The keratinocyte-derived cytokines granulocyte-macrophage-colony-stimulating factor, tumour necrosis factor-alpha, interleukin-6, and interleukin-1 beta...

Topics

Adult
Antigens, CD
Antigens, CD1
Antigens, Surface
Epithelial Cells
Gene Expression Regulation
Gingiva
Granulocyte-Macrophage Colony-Stimulating Factor
Humans
Interleukin-1
Interleukin-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Keratinocytes

Langerhans Cells

Middle Aged

Monocytes

Periodontitis

Phenotype

Stem Cells

Source

Open in PubMed

Identifiers

PMID: 7540833
DOI: 10.1016/0003-9969(94)00152-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7540833-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Induction of the CD1a Langerhans cell marker on human monocytes.PMID 7540833Read ↗

A novel role for Notch ligand Delta-1 as a regulator of human Langerhans cell development from blood monocytes.Semantic proximity Read ↗

Development of a Langerhans cell phenotype from peripheral blood monocytes.Semantic proximity Read ↗

Inverse regulation of the ADAM‐family members, decysin and MADDAM/ADAM19 during monocyte differentiationSemantic proximity Read ↗

Psoriatic lesional keratinocytes promote the maturation of human monocyte-derived Langerhans cells.Semantic proximity Read ↗

Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers.Semantic proximity Read ↗

Transcriptional profiling of human skin-resident Langerhans cells and CD1a+ dermal dendritic cells: differential activation states suggest distinct functions.Semantic proximity Read ↗

Notch-Mediated Generation of Monocyte-Derived Langerhans Cells: Phenotype and Function.Semantic proximity Read ↗

GM-CSF promotes differentiation of a precursor cell of monocytes and Langerhans-type dendritic cells from CD34+ haemopoietic progenitor cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.