Article
Efficient extension of a misaligned tRNA-primer during replication of the HIV-1 retrovirus.
Nucleic acids research - 25 Apr 1995
Das A T, Berkhout B
Abstract excerpt
The human immunodeficiency virus (HIV) and other retroviruses show extensive genomic variation, which is primarily due to error-prone replication by the viral reverse transcriptase (RT) enzymes. RT errors include misincorporation with subsequent extension of the mismatched terminal base, and exte...
Topics
- Base Sequence
- HIV Core Protein p24
- HIV Reverse Transcriptase
- HIV-1
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Proviruses
- RNA
- RNA, Transfer, Lys
- RNA, Viral
- RNA-Directed DNA Polymerase