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Article

Mutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.

Nucleic acids research - 1 Mar 1998

Isel C, Keith G, Ehresmann B, Ehresmann C, Marquet R

Abstract excerpt

Retroviruses use a specific tRNA, whose 3' end is complementary to the 18 nucleotides of the primer binding site (PBS), to prime reverse transcription. Previous work has shown that initiation of HIV-1 reverse transcription is a specific process, in contrast with the subsequent elongation phase. HIV-1 reverse transcriptase (RT) specifically recognizes the complex formed by the viral RNA and tRNA3Lys. We previously...

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Identifiers

PMID: 9469827
DOI: 10.1093/nar/26.5.1198
PMCID: PMC147409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.PMID 9469827Read ↗

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