Article
Melanoma ex naevo: a study of the associated naevus.
Melanoma research - 1 Apr 2003
Bogdan Inja, Smolle Josef, Kerl Helmut, Burg Günther, Böni Roland
Abstract excerpt
It has been shown that the co-occurrence of melanoma and pre-existing naevus is not a random event and that acquired naevi may be precursors of melanoma. A critical area of chromosomal loss at 9p21 has been implicated in the genesis of malignant melanoma, representing a site of frequent somatic chromosomal deletions in melanoma. Allelic deletions within this chromosomal region most often include the tumour...
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