Article
mRNA degradation in Escherichia coli: a novel factor which impedes the exoribonucleolytic activity of PNPase at stem-loop structures.
Molecular microbiology - 1 Nov 1994
Causton H, Py B, McLaren R S, Higgins C F
Abstract excerpt
Stem-loop structures can protect upstream mRNA from degradation by impeding the processive activities of 3'-5' exoribonucleases. The ability of such structures to impede exonuclease activity in vitro is insufficient to account for the stability they can confer on mRNA in vivo. In this study we id...
Topics
- Bacterial Proteins
- Base Sequence
- Cross-Linking Reagents
- DNA, Bacterial
- Escherichia coli
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Polyribonucleotide Nucleotidyltransferase
- RNA, Bacterial