Article
PNPase is a key player in the regulation of small RNAs that control the expression of outer membrane proteins.
RNA (New York, N.Y.) - 1 Mar 2008
Andrade José M, Arraiano Cecília M
Abstract excerpt
In this report, we demonstrate that exonucleolytic turnover is much more important in the regulation of sRNA levels than was previously recognized. For the first time, PNPase is introduced as a major regulatory feature controlling the levels of the small noncoding RNAs MicA and RybB, which are required for the accurate expression of outer membrane proteins (OMPs). In the absence of PNPase, the pattern of OMPs is...
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