Article
Processing of m1 RNA at the 3' end protects its primary transcript from degradation.
The Journal of biological chemistry - 14 Oct 2005
Kim Kwang-Sun, Sim Soyeong, Ko Jae-Hyeong, Lee Younghoon
Abstract excerpt
M1 RNA, the catalytic subunit of Escherichia coli RNase P, is an essential ribozyme that processes the 5' leader sequence of precursor tRNAs. It is generated by the removal of 36 nucleotides from the 3' end of the primary rnpB transcript (pM1 RNA), but the biological significance of this reaction in bacterial metabolism remains obscure. In this study, we constructed and analyzed bacterial strains carrying...
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