Article
PNPase modulates RNase II expression in Escherichia coli: implications for mRNA decay and cell metabolism.
Molecular microbiology - 1 Jun 1996
Zilhão R, Cairrão F, Régnier P, Arraiano C M
Abstract excerpt
PNPase and RNase II are the key regulatory exonucleases controlling mRNA decay in Escherichia coli. The rnb transcripts were found to proceed through the terminator and PNPase was found to be involved in the 3' to 5' degradation of rnb mRNA. Analysis of these longer 3' termini revealed that they are located in UA-rich regions. Comparison of single and double mutants suggested that PNPase and RNase II could have...
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