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Article

3' end mRNA processing: molecular mechanisms and implications for health and disease.

The EMBO journal - 6 Feb 2008

Danckwardt Sven, Hentze Matthias W, Kulozik Andreas E

Abstract excerpt

Recent advances in the understanding of the molecular mechanism of mRNA 3' end processing have uncovered a previously unanticipated integrated network of transcriptional and RNA-processing mechanisms. A variety of human diseases impressively reflect the importance of the precision of the complex 3' end-processing machinery and gene specific deregulation of 3' end processing can result from mutations of RNA...

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Identifiers

PMID: 18256699
DOI: 10.1038/sj.emboj.7601932
PMCID: PMC2241648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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