Article
Allelic loss in chromosomal region 1q21-23 in breast cancer is associated with peritumoral angiolymphatic invasion and extensive intraductal component.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Aug 2000
Gaki V, Tsopanomichalou M, Sourvinos G, Tsiftsis D, Spandidos D A
Abstract excerpt
AIMS: Breast cancer is the most frequent cancer in the female population and the involvement of chromosomal alterations is often implicated in the development of cancer. The aim of our study was to assess loss of heterozygosity (LOH) in chromosome 1 in relation to clinical and pathological parameters. METHODS: Tumours, corresponding normal tissues and peripheral blood samples from 50 women with operable breast...
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