Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the N-terminal part of the neutralizing antigenic site I of coxsackievirus B4 by mutation analysis of antigen chimeras.

Virus research - 1 Nov 1994

McPhee F, Zell R, Reimann B Y, Hofschneider P H, Kandolf R

Abstract excerpt

Coxsackievirus B3 (CVB3) as a potential RNA virus vector for the presentation of foreign antigenic epitopes was further characterized. Insertion mutagenesis of infectious CVB3 cDNA yielded viable antigen chimeras containing variant BC loops of VP1 of coxsackievirus B4 (CVB4). Analysis of three antigen chimeras allowed the mapping of the N-terminal part of the neutralizing antigenic site 1 (N-Ag1) of CVB4 which is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Mutagenesis, Site-Directed

Share to Recombinant Proteins

Share to Transfection

Source

Identifiers

PMID: 7531922
DOI: 10.1016/0168-1702(94)90096-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the N-terminal part of the neutralizing antigenic site I of coxsackievirus B4 by mutation analysis of antigen chimeras.PMID 7531922Read ↗

The construction and characterization of poliovirus antigen chimeras presenting defined regions of the human T lymphocyte marker CD4.Semantic proximity Read ↗

A point mutation in VP1 of coxsackievirus B4 alters antigenicity.Semantic proximity Read ↗

The genetic basis for the antigenicity of the VP2 protein of the infectious bursal disease virus.Semantic proximity Read ↗

Identification of a single amino acid residue in the capsid protein VP1 of coxsackievirus B4 that determines the virulent phenotype.Semantic proximity Read ↗

Antigenic structure of chimeras of type 1 and type 3 poliovirus involving antigenic site 1.Semantic proximity Read ↗

Chimeric rhinoviruses as tools for vaccine development and characterization of protein epitopes.Semantic proximity Read ↗

Identification of a neutralization epitope in the VP1 capsid protein of SV40.Semantic proximity Read ↗

A genetically engineered attenuated coxsackievirus B3 strain protects mice against lethal infection.Semantic proximity Read ↗

A point mutation in the VP4 coding sequence of coxsackievirus B4 influences virulence.Semantic proximity Read ↗

Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis.Semantic proximity Read ↗

T cell epitopes in coxsackievirus B4 structural proteins concentrate in regions conserved between enteroviruses.Semantic proximity Read ↗

Chimeric papillomavirus-like particles expressing a foreign epitope on capsid surface loopsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.