Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic basis for the antigenicity of the VP2 protein of the infectious bursal disease virus.

The Journal of general virology - 1 Aug 1993

Schnitzler D, Bernstein F, Müller H, Becht H

Abstract excerpt

The genomic region coding for the antigenic structure responsible for the induction of neutralizing antibodies was localized in the central variable region of the VP2 gene by comparing the nucleotide sequence of five escape mutants derived from the standard infectious bursal disease virus strain Cu-1. Exchange of a single amino acid at one of the prominent hydrophilic parts of this region proved to be sufficient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Capsid
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Genes, Viral

Share to Molecular Sequence Data

Share to Mutation

Share to Protein Biosynthesis

Source

Identifiers

PMID: 7688411
DOI: 10.1099/0022-1317-74-8-1563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic basis for the antigenicity of the VP2 protein of the infectious bursal disease virus.PMID 7688411Read ↗

Molecular and Structural Bases for the Antigenicity of VP2 of Infectious Bursal Disease VirusSemantic proximity Read ↗

Genetic mechanisms of antigenic variation in infectious bursal disease virus: analysis of a naturally occurring variant virus.Semantic proximity Read ↗

Molecular basis of antigenic variation in infectious bursal disease virusSemantic proximity Read ↗

Identification of crucial residues of conformational epitopes on VP2 protein of infectious bursal disease virus by phage display.Semantic proximity Read ↗

Infectious bursal disease virus: a review of molecular basis for variations in antigenicity and virulence.Semantic proximity Read ↗

Critical amino acid changes in VP2 variable domain are associated with typical and atypical antigenicity in very virulent infectious bursal disease virusesSemantic proximity Read ↗

Heterogeneity of the antigenic site responsible for the induction of neutralizing antibodies in infectious bursal disease virus.Semantic proximity Read ↗

VP2 sequences of recent European 'very virulent' isolates of infectious bursal disease virus are closely related to each other but are distinct from those of 'classical' strains.Semantic proximity Read ↗

Sequence Analysis and Expression of the Host-protective Immunogen VP2 of a Variant Strain of Infectious Bursal Disease Virus Which Can Circumvent Vaccination with Standard Type I StrainsSemantic proximity Read ↗

Antigenic and genetic relationships between European very virulent infectious bursal disease viruses and an early West African isolateSemantic proximity Read ↗

Characterization of the N-terminal part of the neutralizing antigenic site I of coxsackievirus B4 by mutation analysis of antigen chimeras.Semantic proximity Read ↗

Investigation of the antigenic evolution of field isolates using the reverse genetics system of infectious bursal disease virus (IBDV)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.