Article
Chimeric rhinoviruses as tools for vaccine development and characterization of protein epitopes.
Intervirology - 1 Jan 1996
Arnold G F, Resnick D A, Smith A D, Geisler S C, Holmes A K, Arnold E
Abstract excerpt
Chimeric human rhinoviruses (HRVs) have the potential to serve as vaccines against a wide variety of diseases. Such vaccines can be developed optimally by generating libraries of chimeric HRVs displaying immunogens from dangerous pathogens or tumor cells in many different conformations. Extremely large numbers of conformationally defined presentations of foreign epitopes can be produced efficiently by flanking...
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