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Article

Ca++-switch induction of RPE differentiation.

Experimental eye research - 1 Apr 2006

Rak Daniel J, Hardy Katherine M, Jaffe Glenn J, McKay Brian S

Abstract excerpt

Cultured retinal pigment epithelial (RPE) cells are commonly used as a model of the tissue to study their involvement in visual diseases. Unfortunately, cultured RPE often lose their differentiated phenotype reducing their usefulness as a model of the RPE in vivo. In this study, we used a Ca++-switch protocol to initiate the patterned expression of several phenotypic and functional markers of RPE differentiation....

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Identifiers

PMID: 16289163
DOI: 10.1016/j.exer.2005.09.002

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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