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Article

Growth factor regulation of corneal keratocyte mechanical phenotypes in 3-D collagen matrices.

Investigative ophthalmology & visual science - 1 Mar 2012

Lakshman Neema, Petroll W Matthew

Abstract excerpt

PURPOSE: To assess how wound healing cytokines and the extracellular matrix (ECM) environment regulate the keratocyte mechanical phenotype. METHODS: Rabbit corneal keratocytes were plated within standard bovine or rat tail type I collagen matrices (2.5 mg/mL), compressed collagen matrices (approximately 100 mg/mL), or on collagen-coated dishes and cultured for up to 7 days in serum-free media, platelet derived...

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Source

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Identifiers

PMID: 22247479
DOI: 10.1167/iovs.11-8609
PMCID: PMC3339898

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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