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Article

Establishment and characterization of mouse mammary carcinoma cell lines expressing RET with a multiple endocrine neoplasia 2A mutation.

Cancer science - 1 Nov 2003

Kawai Kumi, Jijiwa Mayumi, Shimono Yohei, Kurokawa Kei, Murakumo Yoshiki, Ichihara Masatoshi, Takahashi Masahide

Abstract excerpt

We recently generated transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation (RET-MEN2A). Mammary tumors with frequent lung metastasis were developed in 22% of female transgenic mice in a stochastic fashion. In the current study, we established two cell lines (named MKK-f and MKK-s) from mammary tumors developed in RET-MEN2A transgenic mice. MKK-f and MKK-s were...

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Source

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Identifiers

PMID: 14611677
DOI: 10.1111/j.1349-7006.2003.tb01390.x
PMCID: PMC11160287

Genes

RET

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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