Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Submicroscopic deletions of 3p sequences in pleomorphic adenomas with t(3;8)(p21;q12).

Genes, chromosomes & cancer - 1 Aug 1994

Sahlin P, Mark J, Stenman G

Abstract excerpt

A subgroup of benign pleomorphic adenomas of the salivary glands is characterized by translocations, or on rare occasions deletions, with breakpoints at 3p21. We have applied restriction fragment length polymorphism (RFLP) analysis to assess the frequency of allelic losses at four different loci located within 3p21-->p25 in 35 pleomorphic adenomas, 18 of which were also karyotyped. Parallel analysis of...

Topics

Adenoma, Pleomorphic
Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 3
Chromosomes, Human, Pair 8
Heterozygote
Humans
In Situ Hybridization
Karyotyping
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Salivary Gland Neoplasms

Translocation, Genetic

Source

Identifiers

PMID: 7522539
DOI: 10.1002/gcc.2870100406

Genes

THRB
RAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7522539-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Submicroscopic deletions of 3p sequences in pleomorphic adenomas with t(3;8)(p21;q12).PMID 7522539Read ↗

New genetic findings in parotid gland pleomorphic adenomas.Semantic proximity Read ↗

Deletion at 3p25.3-p23 is frequently encountered in endocrine pancreatic tumours and is associated with metastatic progressionSemantic proximity Read ↗

Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenoma.Semantic proximity Read ↗

Definition of a tumor suppressor gene locus on the short arm of chromosome 3 in squamous cell carcinoma of the head and neck by means of microsatellite markers.Semantic proximity Read ↗

Molecular genetic alterations in carcinoma ex-pleomorphic adenoma: A putative progression model?Semantic proximity Read ↗

Losses of heterozygosity in oral and oropharyngeal epithelial carcinomas.Semantic proximity Read ↗

Mutations associated with carcinomas arising from pleomorphic adenomas of the salivary glands.Semantic proximity Read ↗

PCR-RFLP studies on chromosome 3p in formaldehyde-fixed, paraffin-embedded cervical cancer tissues.Semantic proximity Read ↗

Accumulation of beta-catenin protein, mutations in exon-3 of the beta-catenin gene and a loss of heterozygosity of 5q22 in solid pseudopapillary tumor of the pancreas.Semantic proximity Read ↗

Deletion mapping of the short arm of chromosome 3 in human malignant mesothelioma.Semantic proximity Read ↗

Mapping of chromosome 3p deletions in human epithelial ovarian tumors.Semantic proximity Read ↗

Three distinct regions involved in 3p deletion in human lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.