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Article

Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenoma.

Neoplasia (New York, N.Y.) - 1 Jul 2005

Poetsch Micaela, Zimmermann Anett, Wolf Eduard, Kleist Britta

Abstract excerpt

Pleomorphic adenoma (PA), being the most common benign tumor of the salivary glands, is composed of epithelial and mesenchymal compartments. In this study, we analyzed 19 microsatellite markers from chromosomal arms 6q, 8q, 9p, 12q, and 17p in 31 PAs and 3 carcinoma ex pleomorphic adenomas (CXPAs) as well as 11 other non-PA-related carcinomas of the salivary gland for comparison. In our analysis, we...

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PMID: 16026648
DOI: 10.1593/neo.05163
PMCID: PMC1501429

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