Article
Mutagenesis of yeast MW104-1B strain has identified the uncharacterized PMS6 DNA mismatch repair gene locus and additional alleles of existing PMS1, PMS2 and MSH2 genes.
Mutation research - 1 Sept 1994
Jeyaprakash A, Welch J W, Fogel S
Abstract excerpt
The haploid yeast Saccharomyces cerevisiae MW104-1B strain was disomic for chromosome III (n + 1) and carried DNA mismatches at three different heteroallelic loci; leu2 (leu2-1/leu2-27), thr4 (thr4-1/thr4-16) and his4 (his4-4/his4-519) (Williamson, 1984). We mutagenized the MW104-1B strain and id...
Topics
- Alleles
- Chromosomes, Fungal
- DNA Repair
- DNA Replication
- DNA, Fungal
- Ethyl Methanesulfonate
- Gene Conversion
- Genes, Fungal
- Genetic Complementation Test
- Meiosis
- Mutagenesis
- Nucleic Acid Heteroduplexes
- Saccharomyces cerevisiae