Article
Analysis of yeast pms1, msh2, and mlh1 mutators points to differences in mismatch correction efficiencies between prokaryotic and eukaryotic cells.
Molecular & general genetics : MGG - 1 Jun 1999
Yang Y, Karthikeyan R, Mack S E, Vonarx E J, Kunz B A
Abstract excerpt
Genetic stability relies in part on the efficiency with which post-replicative mismatch repair (MMR) detects and corrects DNA replication errors. In Escherichia coli, endogenous transition mispairs and insertion/deletion (ID) heterologies are corrected with similar efficiencies--but much more efficiently than transversion mispairs--as revealed by mutation rate increases in MMR mutants. To assess the relative...
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