Article
Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes.
Genetics - 1 Nov 2002
Welz-Voegele Caroline, Stone Jana E, Tran Phuoc T, Kearney Hutton M, Liskay R Michael, Petes Thomas D, Jinks-Robertson Sue
Abstract excerpt
Mismatch-repair (MMR) systems promote eukaryotic genome stability by removing errors introduced during DNA replication and by inhibiting recombination between nonidentical sequences (spellchecker and antirecombination activities, respectively). Following a common mismatch-recognition step effected by MutS-homologous Msh proteins, homologs of the bacterial MutL ATPase (predominantly the Mlh1p-Pms1p heterodimer in...
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