Article
Defective transformation of chromosomal markers in DNA polymerase I mutants of the radioresistant bacterium Deinococcus radiodurans.
Mutation research - 1 Sept 1994
Fuchs P, Agostini H, Minton K W
Abstract excerpt
The transformation efficiency of six independently selected chromosomal markers (four for rifampicin resistance and two for acriflavine resistance) was found to be reduced by about 3 logs in a Deinococcus radiodurans strain that was isogenic with wild type except for an insertional mutation in the pol gene that eliminated DNA polymerase I activity (strain 6R1A). D. radiodurans strains UV17 and 303, previously...
Topics
- Acriflavine
- Chloramphenicol
- DNA Damage
- DNA Polymerase I
- Gamma Rays
- Genes, Bacterial
- Genetic Markers
- Genotype
- Gram-Positive Cocci
- Kanamycin
- Models, Genetic