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Article

Developing a genetic system in Deinococcus radiodurans for analyzing mutations.

Genetics - 1 Feb 2004

Kim Mandy, Wolff Erika, Huang Tiffany, Garibyan Lilit, Earl Ashlee M, Battista John R, Miller Jeffrey H

Abstract excerpt

We have applied a genetic system for analyzing mutations in Escherichia coli to Deinococcus radiodurans, an extremeophile with an astonishingly high resistance to UV- and ionizing-radiation-induced mutagenesis. Taking advantage of the conservation of the beta-subunit of RNA polymerase among most prokaryotes, we derived again in D. radiodurans the rpoB/Rif(r) system that we developed in E. coli to monitor base...

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Identifiers

PMID: 15020457
DOI: 10.1534/genetics.166.2.661
PMCID: PMC1470732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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