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Article

Identification of new genes contributing to the extreme radioresistance of Deinococcus radiodurans using a Tn5-based transposon mutant library.

PloS one - 1 Jan 2015

Dulermo Rémi, Onodera Takefumi, Coste Geneviève, Passot Fanny, Dutertre Murielle, Porteron Martine, Confalonieri Fabrice, Sommer Suzanne, Pasternak Cécile

Abstract excerpt

Here, we have developed an extremely efficient in vivo Tn5-based mutagenesis procedure to construct a Deinococcus radiodurans insertion mutant library subsequently screened for sensitivity to genotoxic agents such as γ and UV radiations or mitomycin C. The genes inactivated in radiosensitive mutants belong to various functional categories, including DNA repair functions, stress responses, signal transduction,...

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Source

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Identifiers

PMID: 25884619
DOI: 10.1371/journal.pone.0124358
PMCID: PMC4401554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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