Article
Novel ionizing radiation-sensitive mutants of Deinococcus radiodurans.
Journal of bacteriology - 1 Dec 1994
Udupa K S, O'Cain P A, Mattimore V, Battista J R
Abstract excerpt
Two new loci, irrB and irrI, have been identified in Deinococcus radiodurans. Inactivation of either locus results in a partial loss of resistance to ionizing radiation. The magnitude of this loss is locus specific and differentially affected by inactivation of the uvrA gene product. An irrB uvrA double mutant is more sensitive to ionizing radiation than is an irrB mutant. In contrast, the irrI uvrA double mutant...
Topics
- Adenosine Triphosphatases
- Bacterial Proteins
- DNA, Bacterial
- DNA-Binding Proteins
- Dose-Response Relationship, Radiation
- Drug Resistance, Microbial
- Escherichia coli Proteins
- Gamma Rays
- Genomic Library
- Gram-Positive Cocci