Article
Involvement of a protein kinase activity inducer in DNA double strand break repair and radioresistance of Deinococcus radiodurans.
Journal of bacteriology - 1 Jun 2008
Rajpurohit Yogendra S, Gopalakrishnan Roja, Misra Hari S
Abstract excerpt
Transgenic bacteria producing pyrroloquinoline quinone, a known cofactor for dehydrogenases and an inducer of a periplasmic protein kinase activity, show resistance to both oxidative stress and protection from nonoxidative effects of radiation and DNA-damaging agents. Deinococcus radiodurans R1 encodes an active pyrroloquinoline quinone synthase, and constitutive synthesis of pyrroloquinoline quinone occurred in...
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