Article
Mismatch repair ensures fidelity of replication and recombination in the radioresistant organism Deinococcus radiodurans.
Molecular genetics and genomics : MGG - 1 Nov 2004
Mennecier S, Coste G, Servant P, Bailone A, Sommer S
Abstract excerpt
We have characterized the mismatch repair system (MMR) of the highly radiation-resistant type strain of Deinococcus radiodurans, ATCC 13939. We show that the MMR system is functional in this organism, where it participates in ensuring the fidelity of DNA replication and recombination. The system relies on the activity of two key proteins, MutS1 and MutL, which constitute a conserved core involved in mismatch...
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