Characterization in vitro and in vivo of the DNA helicase encoded by Deinococcus radiodurans locus DR1572.

doi:10.1016/j.dnarep.2008.12.011

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Article

Characterization in vitro and in vivo of the DNA helicase encoded by Deinococcus radiodurans locus DR1572.

DNA repair - 1 May 2009

Cao Zheng, Julin Douglas A

Abstract excerpt

Deinococcus radiodurans survives extremely high doses of ionizing and ultraviolet radiation and treatment with various DNA-damaging chemicals. As an effort to identify and characterize proteins that function in DNA repair in this organism, we have studied the protein encoded by locus DR1572. This gene is predicted to encode a Superfamily I DNA helicase, except that genome sequencing indicated that it has a...

Topics

Adenosine Triphosphate
Amino Acid Sequence
Antineoplastic Agents, Alkylating
Bacterial Proteins
Blotting, Southern
Cloning, Molecular
DNA Damage
DNA Helicases
DNA Repair
Deinococcus
Gamma Rays
Hydrogen Peroxide
Hydrolysis
In Vitro Techniques
Methyl Methanesulfonate
Mitomycin
Molecular Sequence Data
Mutation

Source

Open in PubMed

Identifiers

PMID: 19179120
DOI: 10.1016/j.dnarep.2008.12.011

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