Role of polyadenylated RNA sequences (POLADS) in vaccinia virus infection: correlation between accumulation of POLADS and extent of shut-off in infected cells.

Abstract excerpt

The selective inhibition of host-cell protein synthesis was studied in cells infected with vaccinia virus (VV) under aberrant conditions of transcription. Previous studies in our laboratory have correlated this selective inhibition with a class of short polyadenylated virus-directed RNAs (POLADS) which are synthesized in VV-infected cells during the early phase of transcription. Moreover, it was shown that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mice
• Share to Mutation
• Share to Protein Biosynthesis