Article
Transient expression of the vaccinia virus DNA polymerase is an intrinsic feature of the early phase of infection and is unlinked to DNA replication and late gene expression.
Journal of virology - 1 Jan 1992
McDonald W F, Crozel-Goudot V, Traktman P
Abstract excerpt
We have studied the expression pattern of the vaccinia virus DNA polymerase during the viral replicative cycle. To monitor polymerase synthesis, a polyclonal antiserum was raised against a TrpE-DNA polymerase fusion protein. Immunoprecipitation and S1 analyses revealed that polymerase synthesis a...
Topics
- Animals
- Antibody Specificity
- Base Sequence
- Cycloheximide
- DNA Replication
- DNA, Viral
- DNA-Directed DNA Polymerase
- Gene Expression Regulation, Viral
- L Cells
- Mice
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Transcription, Genetic
- Vaccinia virus