Effects of signalling transduction modulators on the transformed phenotypes in v-H-ras-transformed NIH 3T3 cells.

doi:10.1016/0304-3835(93)90243-3

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Article

Effects of signalling transduction modulators on the transformed phenotypes in v-H-ras-transformed NIH 3T3 cells.

Cancer letters - 1 Nov 1993

Kuo M L, Kang J J, Yang N C

Abstract excerpt

Several signalling transduction modulators were used to examine their effects on the morphological changes, foci formation in soft agar and cellular growth in v-H-ras-transformed NIH 3T3 cells. The results from this study showed that specific tyrosine kinase inhibitors (genistein and tyrphostin 2...

Topics

1-Methyl-3-isobutylxanthine
3T3 Cells
Animals
Catechols
Colforsin
Genes, ras
Genistein
Isoflavones
Mice
Nitriles
Phenotype
Signal Transduction
Tyrphostins

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