Reversion of the transformed phenotypes of v-H-ras NIH3T3 cells by flavonoids through attenuating the content of phosphotyrosine.

doi:10.1016/0304-3835(94)90414-6

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Article

Reversion of the transformed phenotypes of v-H-ras NIH3T3 cells by flavonoids through attenuating the content of phosphotyrosine.

Cancer letters - 25 Nov 1994

Kuo M L, Lin J K, Huang T S, Yang N C

Abstract excerpt

Fifteen flavonoids were employed to examine their effects on the morphological changes, foci formation in soft agar and cellular growth in v-H-ras-transformed NIH3T3 cells. The data presented here demonstrated that only three specific flavonoids--apigenin, kaempferol, and genistein--exhibited the...

Topics

3T3 Cells
Animals
Cell Division
Cell Line, Transformed
Cell Transformation, Neoplastic
Cell Transformation, Viral
Chamomile
Culture Media
Cyclic AMP
Dose-Response Relationship, Drug
Flavonoids
Genes, ras

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genistein

Isoflavones

Kaempferols

Mice

Oils, Volatile

Phenotype

Source

Open in PubMed

Identifiers

PMID: 7525047
DOI: 10.1016/0304-3835(94)90414-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7525047-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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