Preneoplastic potential of morphologically distinct transformed foci induced by 3-methylcholanthrene.

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Article

Preneoplastic potential of morphologically distinct transformed foci induced by 3-methylcholanthrene.

Environmental and molecular mutagenesis - 1 Jan 1998

Keshava N, Keshava C, Whong W Z, Hubbs A F, Nath J, Ong T

Abstract excerpt

Individual variability of scoring foci positive for transformation presents a difficult problem in assessing the transformation assay. In this study, an attempt was made to identify five morphologically distinct types of transformed foci based on size (2-3, 3-4, and > or = 4 mm in diameter), inva...

Topics

3T3 Cells
Animals
Blotting, Southern
Carcinogens
Cell Transformation, Neoplastic
Clone Cells
Methylcholanthrene
Mice
Mice, Inbred BALB C
Mutagens
Mutation
Precancerous Conditions
Proto-Oncogenes
Transfection

Source

Open in PubMed

Identifiers

PMID: 9882012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9882012-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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