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Article

Preneoplastic potential of morphologically distinct transformed foci induced by 3-methylcholanthrene.

Environmental and molecular mutagenesis - 1 Jan 1998

Keshava N, Keshava C, Whong W Z, Hubbs A F, Nath J, Ong T

Abstract excerpt

Individual variability of scoring foci positive for transformation presents a difficult problem in assessing the transformation assay. In this study, an attempt was made to identify five morphologically distinct types of transformed foci based on size (2-3, 3-4, and > or = 4 mm in diameter), invasiveness (smooth vs. invading margins), and other properties (piling vs. spread) induced by 3-methylcholanthrene in...

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PMID: 9882012

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