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Article

Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB.

Journal of cellular physiology - 1 Sept 2001

Rosenmüller T, Rydh K, Nånberg E

Abstract excerpt

Phosphoinositide 3OH-kinases (PI3K) are a family of lipid kinases that activates signalling pathways important for migration, cytoskeletal rearrangements, and cell survival. These processes are important hallmarks in transformation. We have evaluated the functional role of PI3K for development of a transformed morphology and migratory responses of murine fibroblasts (NIH/sis and COL1A1/NIH3T3 cell lines)...

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Identifiers

PMID: 11473364
DOI: 10.1002/jcp.1126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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