Article
Defining rules for the peptide-MHC class II interaction.
Current opinion in immunology - 1 Feb 1994
Sinigaglia F, Hammer J
Abstract excerpt
Recent work has begun to clarify the molecular events governing peptide interaction with MHC class II proteins. The requirements for peptide binding to class I and class II molecules seem to be similar. Despite differences in peptide length, anchor residues defining allele-specific peptide motifs can also be found in class II binding peptides. The presence of conserved and allele-specific anchors appears to...
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