Article
Class I MHC-peptide interactions: structural requirements and functional implications.
Cancer surveys - 1 Jan 1995
Grey H M, Ruppert J, Vitiello A, Sidney J, Kast W M, Kubo R T, Sette A
Abstract excerpt
In this chapter, we have defined the structural motifs that dictate the capacity of peptides to bind to five different HLA-A alleles that represent some of the most common alleles found in different ethnic populations. In general, these peptide motifs were very specific for the individual HLA-A alleles, with the exception of HLA-A degree 0301 and HLA-A degree 1101, for which the motifs were very similar. When...
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