Article
Class I MHC-peptide interactions: structural requirements and functional implications.
Cancer surveys - 1 Jan 1995
Grey H M, Ruppert J, Vitiello A, Sidney J, Kast W M, Kubo R T, Sette A
Abstract excerpt
In this chapter, we have defined the structural motifs that dictate the capacity of peptides to bind to five different HLA-A alleles that represent some of the most common alleles found in different ethnic populations. In general, these peptide motifs were very specific for the individual HLA-A a...
Topics
- Alleles
- Amino Acid Sequence
- Epitopes
- Ethnicity
- Genes, MHC Class I
- HLA-A Antigens
- Humans
- Molecular Sequence Data
- Peptides
- Receptors, Antigen, T-Cell
- T-Lymphocytes, Cytotoxic