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Article

[Reverse transcriptase gene analysis of HIV-1 mutants cultured in the presence of AZT].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases - 1 Oct 1993

Kondo M, Saito T, Ito A, Oka S, Hamamoto K, Imai M

Abstract excerpt

HIV-1 strains were isolated from four patients treated with AZT for more than 6 months and from three patients untreated with AZT. Isolates from patients treated with AZT have been cultured by passage of virus in cell culture in the presence of 1 microM AZT. However the isolates from patients untreated with AZT could not be cultured in the presence of AZT. The RT gene of HIV-1 isolates which had been cultured in...

Topics

Amino Acid Sequence
DNA Mutational Analysis
Drug Resistance, Microbial
Female
Genes, Viral
HIV Reverse Transcriptase
HIV-1
Humans
Male
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

RNA-Directed DNA Polymerase

Zidovudine

Source

Identifiers

PMID: 7504715
DOI: 10.11150/kansenshogakuzasshi1970.67.992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7504715-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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