Article
[Reverse transcriptase gene analysis of HIV-1 mutants cultured in the presence of AZT].
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases - 1 Oct 1993
Kondo M, Saito T, Ito A, Oka S, Hamamoto K, Imai M
Abstract excerpt
HIV-1 strains were isolated from four patients treated with AZT for more than 6 months and from three patients untreated with AZT. Isolates from patients treated with AZT have been cultured by passage of virus in cell culture in the presence of 1 microM AZT. However the isolates from patients untreated with AZT could not be cultured in the presence of AZT. The RT gene of HIV-1 isolates which had been cultured in...
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