Article
Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.
Genetics - 1 Aug 1995
West M L, Corden J L
Abstract excerpt
The carboxyl-terminal domain (CTD) of the RNA polymerase II largest subunit plays an essential but poorly understood role in transcription. The CTD is highly phosphorylated in vivo and this modification may be important in the transition from transcription initiation to elongation. We report here the development of a strategy for creating novel yeast CTDs. We have used this approach to show that the minimum...
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