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Article

Repeat-Specific Functions for the C-Terminal Domain of RNA Polymerase II in Budding Yeast.

G3 (Bethesda, Md.) - 4 May 2018

Babokhov Michael, Mosaheb Mohammad M, Baker Richard W, Fuchs Stephen M

Abstract excerpt

The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (RNAPII) is required to regulate transcription and to integrate it with other essential cellular processes. In the budding yeast Saccharomyces cerevisiae, the CTD of Rpb1p consists of 26 conserved heptad repeats that are post-translationally modified to orchestrate protein factor binding at different stages of the transcription cycle. A...

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Identifiers

PMID: 29523636
DOI: 10.1534/g3.118.200086
PMCID: PMC5940151

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Source receipt: pubmed, retrieved 7 Sept 2026.

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