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Article

Function and control of RNA polymerase II C-terminal domain phosphorylation in vertebrate transcription and RNA processing.

Molecular and cellular biology - 1 Jul 2014

Hsin Jing-Ping, Xiang Kehui, Manley James L

Abstract excerpt

The C-terminal domain of the RNA polymerase II largest subunit (the Rpb1 CTD) is composed of tandem heptad repeats of the consensus sequence Y(1)S(2)P(3)T(4)S(5)P(6)S(7). We reported previously that Thr 4 is phosphorylated and functions in histone mRNA 3'-end formation in chicken DT40 cells. Here, we have extended our studies on Thr 4 and to other CTD mutations by using these cells. We found that an Rpb1...

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Identifiers

PMID: 24752900
DOI: 10.1128/MCB.00181-14
PMCID: PMC4054314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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