Article
Microsatellite instability and other molecular abnormalities in non-small cell lung cancer.
Cancer research - 1 Jan 1995
Fong K M, Zimmerman P V, Smith P J
Abstract excerpt
Microsatellites are highly polymorphic, short-tandem repeat sequences dispersed throughout the genome. Instability of these repeat sequences at multiple genetic loci may result from mismatch repair errors and occur in hereditary nonpolyposis colorectal carcinoma and certain sporadic cancers. In non-small cell lung cancer, we found that microsatellite instability was infrequent, affecting only 7 (6.5%) of 108...
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