Microsatellite instability and other molecular abnormalities in non-small cell lung cancer.

Article

Microsatellite instability and other molecular abnormalities in non-small cell lung cancer.

Cancer research - 1 Jan 1995

Fong K M, Zimmerman P V, Smith P J

Abstract excerpt

Microsatellites are highly polymorphic, short-tandem repeat sequences dispersed throughout the genome. Instability of these repeat sequences at multiple genetic loci may result from mismatch repair errors and occur in hereditary nonpolyposis colorectal carcinoma and certain sporadic cancers. In n...

Topics

Aged
Base Sequence
Carcinoma, Non-Small-Cell Lung
Chromosome Deletion
DNA, Satellite
Female
Genes, p53
Genes, ras
Humans
Lung Neoplasms
Male
Middle Aged
Molecular Sequence Data
Mutation

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