Article
Microsatellite instability in adenocarcinoma of the prostate.
The American journal of pathology - 1 Sept 1995
Terrell R B, Wille A H, Cheville J C, Nystuen A M, Cohen M B, Sheffield V C
Abstract excerpt
Instability of dinucleotide tandem repeat sequences has been reported to play a major role in the carcinogenic pathway of familial colon cancer, as well as a potential role in the carcinogenesis of other sporadic neoplasms. To determine the frequency of short tandem repeat instability in adenocarcinoma of the prostate, we studied 40 tumors that were stratified according to tumor grade. The tissue samples were...
Topics
- Adenocarcinoma
- Base Sequence
- DNA, Neoplasm
- DNA, Satellite
- Humans
- Male
- Molecular Sequence Data
- Phenotype
- Prostatic Neoplasms