Article
Yeast Num1p associates with the mother cell cortex during S/G2 phase and affects microtubular functions.
The Journal of cell biology - 1 Nov 1995
Farkasovsky M, Küntzel H
Abstract excerpt
The NUM1 gene is involved in the control of nuclear migration in Saccharomyces cerevisiae. The content of NUM1 mRNA fluctuates during the cell cycle, reaching a maximum at S/G2 phase, and the translation product Num1p associates with the cortex of mother cells mainly during S, G2, and mitosis, as seen by indirect immunofluorescence. The nuclear spindle in NUM1-deficient large-budded cells often fails to align...
Topics
- Calcium-Binding Proteins
- Cell Membrane
- Cell Nucleus
- Cytoskeletal Proteins
- Fluorescent Antibody Technique, Indirect
- Fungal Proteins
- G2 Phase
- Microscopy, Phase-Contrast
- Microtubules
- Mutation
- Periodicity
