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Article

Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria.

Proceedings of the National Academy of Sciences of the United States of America - 5 Feb 2013

Lackner Laura L, Ping Holly, Graef Martin, Murley Andrew, Nunnari Jodi

Abstract excerpt

To elucidate the functional roles of mitochondrial dynamics in vivo, we identified genes that become essential in cells lacking the dynamin-related proteins Fzo1 and Dnm1, which are required for mitochondrial fusion and division, respectively. The screen identified Num1, a cortical protein implicated in mitochondrial division and distribution that also functions in nuclear migration. Our data indicate that Num1,...

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Identifiers

PMID: 23341591
DOI: 10.1073/pnas.1215232110
PMCID: PMC3568303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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