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Article

Fission yeast Num1p is a cortical factor anchoring dynein and is essential for the horse-tail nuclear movement during meiotic prophase.

Genetics - 1 Jul 2006

Yamashita Akira, Yamamoto Masayuki

Abstract excerpt

During meiotic prophase in the fission yeast Schizosaccharomyces pombe, the nucleus oscillates between the two ends of a cell. This oscillatory nuclear movement is important to promote accurate pairing of homologous chromosomes and requires cytoplasmic dynein. Dynein accumulates at the points where microtubule plus ends contact the cell cortex and generate a force to drive nuclear oscillation. However, it remains...

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Identifiers

PMID: 16624923
DOI: 10.1534/genetics.105.050062
PMCID: PMC1526665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fission yeast Num1p is a cortical factor anchoring dynein and is essential for the horse-tail nuclear movement during meiotic prophase.PMID 16624923Read ↗

The cortical protein Num1p is essential for dynein-dependent interactions of microtubules with the cortex.Semantic proximity Read ↗

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A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioning.Semantic proximity Read ↗

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Yeast Num1p associates with the mother cell cortex during S/G2 phase and affects microtubular functions.Semantic proximity Read ↗

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Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells.Semantic proximity Read ↗

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