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Article

Fos is an essential component of the mammalian UV response.

The EMBO journal - 1 Nov 1995

Schreiber M, Baumann B, Cotten M, Angel P, Wagner E F

Abstract excerpt

Mouse 3T3 fibroblasts lacking c-fos were employed to demonstrate an essential function of the UV-inducible transcription factor AP-1 (Fos/Jun) in the response to the cytotoxic effects of short-wavelength ultraviolet (UVC) radiation. Clonogenic survival and proliferation of cells lacking c-fos were drastically reduced following UV irradiation. This UV hypersensitivity manifests itself primarily in increased cell...

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Identifiers

PMID: 7489723
DOI: 10.1002/j.1460-2075.1995.tb00218.x
PMCID: PMC394643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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