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Article

Fos is an essential component of the mammalian UV response.

The EMBO journal - 1 Nov 1995

Schreiber M, Baumann B, Cotten M, Angel P, Wagner E F

Abstract excerpt

Mouse 3T3 fibroblasts lacking c-fos were employed to demonstrate an essential function of the UV-inducible transcription factor AP-1 (Fos/Jun) in the response to the cytotoxic effects of short-wavelength ultraviolet (UVC) radiation. Clonogenic survival and proliferation of cells lacking c-fos wer...

Topics

3T3 Cells
Animals
Apoptosis
Base Sequence
Cell Cycle
Cell Division
DNA Repair
Genes, fos
Mice
Molecular Sequence Data
Mutation
Transcription Factor AP-1
Ultraviolet Rays

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Identifiers

PMID: 7489723
DOI: 10.1002/j.1460-2075.1995.tb00218.x
PMCID: PMC394643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7489723-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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